The match will begin at 1.30 PM.
Star all-rounder Hardik Pandya will be leading the hosts in the absence of Rohit Sharma.
With the ODI World Cup to be held later in the year, the men-in-blue would aim to start the ODI series with a victory.
India is currently is top-ranked in the ODI rankings, while Australia is at second place.
After the ODIs against Australia end on March 22, all players will go to join their respective IPL teams for the tournament from March 31 to May 28, which will be followed by the World Test Championship final from June 7-11 at The Oval, where India will face Australia.
Also Read: IND v AUS: Ishan, Shubman to be opening pair, says Hardik Pandya
India: Shubman Gill, Ishan Kishan(w), Virat Kohli, Suryakumar Yadav, KL Rahul, Hardik Pandya(c), Ravindra Jadeja, Washington Sundar, Mohammed Shami, Mohammed Siraj, Yuzvendra Chahal, Shardul Thakur, Axar Patel, Kuldeep Yadav, Umran Malik, Jaydev Unadkat
Australia: David Warner, Travis Head, Steven Smith(c), Marnus Labuschagne, Glenn Maxwell, Alex Carey(w), Cameron Green, Ashton Agar, Sean Abbott, Mitchell Starc, Adam Zampa, Mitchell Marsh, Marcus Stoinis, Josh Inglis, Nathan Ellis.